Figure 3.

The model reproduces overexpression phenotypes of frq, wc-1, and csp-1. (A) Clock period as a function of the rate of frq overexpression, k₀₁ in wild-type genetic background. (B) Clock period as a function of wc-1 overexpression rate, k₀₃, in wild-type genetic background. (C) Clock period as a function of wc-1 overexpression rate, k₀₃, in wc-1^ko genetic background (the wc-1 expression rate constant k₇ = 0). (D) Clock period as a function of k₀₄, simulating the rate of csp-1 overexpression in qa-2 promoter knock-in experiment (the csp-1 expression rate constant k₁₆ = 0).