Figure 6.

Ramachandran angles for the samples in water (a, c, and e) and 2 M glucose (b, d, and f). Samples included AAAAA (a and b), desmosine with alanine (c and d), and isodesmosine residues with alanine (e and f) (alanine Ramachandran angles are shown). The angles were calculated using the final 1 ns of the 20 ns simulations (images are shown in color). Note that for AAAAA in glucose, there is a change or increase from β-spiral to α-helical, consistent with the experimental NMR results. A schematic representation of the desmosine and isodesmosine molecules used in the simulations is shown in Fig. S1. To see this figure in color, go online.