Table 1.
Baseline Patient Characteristics
| LVESVi Change at 6 Months |
||||
|---|---|---|---|---|
| Increased or decreased <15% (n = 170) | Decreased ≥15% (n = 183) | All Patients (n = 353) | p-value | |
| Age, mean (yrs) | 63.8 ± 9.4 | 62.2 ± 11.5 | 63.0 ± 10.6 | 0.15 |
| Male (%) | 148 (87.1) | 122 (66.7) | 270 (76.5) | < 0.0001 |
| Ischemic etiology (%) | 117 (68.8) | 83 (45.4) | 200 (56.7) | < 0.0001 |
| CRT-D (%) | 151 (88.8) | 139 (76.0) | 290 (82.2) | 0.002 |
| NYHA II (%) | 135 (79.4) | 152 (83.1) | 287 (81.3) | 0.41 |
| LBBB | 80 (47.3) | 137 (75.7) | 217 (62.0) | < 0.0001 |
| RBBB | 24 (14.2) | 6 (3.3) | 30 (8.6) | |
| IVCD | 65 (38.5) | 38 (21.0) | 103 (29.4) | |
| LVEF (%) | 26.4 ± 7.3 | 27.2 ± 6.7 | 26.8 ± 7.0 | 0.26 |
| LVESVi (ml/m2) | 97.9 ± 35.7 | 100.8 ± 33.9 | 99.4 ± 34.7 | 0.42 |
| QRS (ms) | 148 ± 20 | 157 ± 21 | 153 ± 20 | < 0.0001 |
| Diabetes (%) | 44 (25.9) | 33 (18.0) | 77 (21.8) | 0.09 |
| ACE Inhibitor or ARB (%) | 163 (95.9) | 177 (96.7) | 340 (96.3) | 0.78 |
| Beta-blocker (%) | 160 (94.1) | 175 (95.6) | 335 (94.9) | 0.63 |
| Diuretics (%) | 137 (80.6) | 144 (78.7) | 281 (79.6) | 0.69 |
Values are presented as n (%). Continuous variables are represented by mean ± standard deviation. Student's t-test or Fisher's exact test are used to test for statistical significance between groups in the first 2 columns.
ACE = angiotensin-converting enzyme; ARB = angiotensin receptor blockers;CRT-D = cardiac resynchronization therapy with implantable defibrillator; IVCD = interventricular conduction delay; LBBB = left bundle branch block; LVEF = left ventricular ejection fraction;LVESVi = left ventricular end-systolic volume index; NYHA = New York Heart Association; RBBB = right bundle-branch block.