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. 2014 Jul 4;27(6):824–832. doi: 10.1007/s10278-014-9707-y

Table 3.

Summary of the coefficient of determination (R 2) for the three ROI placement methods and different models

ROI placement No. of variables First-order model Second-order model Second-order model with interactions
Method 1 133 0.65 0.76 0.79
Method 2 89 0.36 0.36 0.57
Method 3 89 0.55 0.68 0.82a

ROI region of interest

aThe best result (highest correlation) in each row and column was using method 3