Figure 2.
Impact of the underlying mean intensive care unit (ICU) daily cost level on the total ICU cost difference between dexmedetomidine (D) and standard care (SC). The three ICU period-specific daily costs were varied up or down from the base case values that reflected an overall mean cost of €1,702 per ICU day (triangle). Alternative period-specific unit costs reflecting a mean cost range between €500 and €3,100 per ICU day were tested. Negative values indicate lower costs on dexmedetomidine. For a conservative approach, the standard sedative acquisition costs were set to zero.