Table 3.
Platelet parameters in blood samples incubated with carbon black nanomaterial
| Parameter | Sample | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | AVG | STD | p | P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLT (109 cells/L) | A | 106 | 71 | 91 | 62 | 56 | 69 | 169 | - | 114 | 146 | 114 | 109 | 38 | 37 | 89.4 | 39.0 | 0.16 (A-C) | |
| B | 61 | 56 | 99 | 80 | 49 | 104 | 176 | 56 | 123 | 184 | 92 | 119 | 99.9 | 44.9 | 0.21 (B-C) | ||||
| C | 117 | 82 | 129 | 86 | 56 | 117 | 182 | 104 | 121 | 209 | 141 | 129 | 49 | 59 | 113 | 45.9 | 0.91 (A-B) | ||
| PCT (%) | A | 0.1 | 0.07 | 0.09 | 0.07 | 0.05 | 0.07 | 0.16 | 0.06 | 0.11 | 0.13 | 0.1 | 0.1 | 0.04 | 0.03 | 0.08 | 0.04 | 0.21 (A-C) | |
| B | 0.06 | 0.06 | 0.1 | 0.08 | 0.05 | 0.1 | 0.17 | 0.05 | 0.12 | 0.16 | 0.08 | 0.11 | 0.10 | 0.04 | 0.31 (B-C) | ||||
| C | 0.11 | 0.08 | 0.13 | 0.08 | 0.05 | 0.11 | 0.16 | 0.09 | 0.11 | 0.17 | 0.12 | 0.12 | 0.05 | 0.05 | 0.10 | 0.04 | 0.87 (A-B) | ||
| MPV (fL) | A | 9.5 | 10.5 | 9.9 | 10.5 | 9.2 | 9.7 | 9.4 | 9.2 | 9.6 | 8.6 | 9 | 8.9 | 9.4 | 8.3 | 9.41 | 0.63 | 0.62 (A-C) | |
| B | 10 | 10.5 | 10.2 | 9.9 | 9.3 | 9.6 | 9.6 | 8.8 | 9.6 | 8.4 | 8.7 | 9.4 | 9.5 | 0.63 | 0.39 (B-C) | ||||
| C | 9.5 | 10.3 | 10.1 | 9.7 | 9 | 9.5 | 8.8 | 8.7 | 9 | 8.4 | 8.8 | 9.6 | 9.7 | 9 | 9.29 | 0.56 | 1.00 (A-B) | ||
| PDW (%) | A | 56 | 63.8 | 57.6 | 65.4 | 72.2 | 61.3 | 62.1 | 67.7 | 59.1 | 54 | 61.9 | 53.8 | 51.6 | 47.7 | 59.6 | 6.67 | 0.15 (A-C) | |
| B | 61.5 | 61.0 | 59.7 | 56.8 | 63.2 | 61.8 | 61.8 | 54.5 | 56.8 | 55.4 | 47.2 | 60 | 58.3 | 4.49 | 0.31 (B-C) | ||||
| C | 54.6 | 62.3 | 55.4 | 54 | 60.2 | 58.1 | 58.3 | 59.7 | 52.9 | 52.4 | 60 | 50.9 | 56.3 | 57.8 | 56.6 | 3.39 | 0.17 (A-B) | ||
| MPC (g/L) | A | 215 | 211 | 216 | 209 | 223 | 222 | 228 | 209 | 215 | 219 | 219 | 229 | 206 | 174 | 214 | 13.4 | 0.02 (A-C) | 0.88 |
| B | 189 | 206 | 219 | 215 | 218 | 236 | 218 | 212 | 220 | 220 | 209 | 229 | 216 | 11.7 | 0.00 (B-C) | 0.84 | |||
| C | 214 | 225 | 222 | 232 | 226 | 239 | 232 | 233 | 230 | 230 | 229 | 229 | 219 | 193 | 225 | 11.2 | 0.61 (A-B) | ||
| MPM (pg) | A | 1.89 | 1.99 | 1.95 | 0.96 | 1.81 | 1.97 | 1.97 | 1.74 | 1.88 | 2.74 | 1.79 | 1.89 | 1.78 | 1.38 | 1.84 | 0.38 | 0.45 (A-C) | |
| B | 1.72 | 1.96 | 2.01 | 1.94 | 1.84 | 2.06 | 1.91 | 1.73 | 1.92 | 1.71 | 1.72 | 1.89 | 1.87 | 0.12 | 0.10 (B-C) | ||||
| C | 1.88 | 2.09 | 2.04 | 2.07 | 1.86 | 2.1 | 1.89 | 1.87 | 1.92 | 1.77 | 1.86 | 2.03 | 1.92 | 1.6 | 1.92 | 0.14 | 0.90 (A-B) |
Platelet parameters (Platelet count (PLT), plateletcrit (PCT), platelet distribution width (PDW), mean platelet volume (MPV), mean platelet mass (MPM) and mean platelet component (MPC)) in blood samples incubated with two different carbon black nanomaterial concentrations (A – 0.5 mg/mL, B – 1 mg/mL), and control suspension incubated with citrated and phosphate-buffered saline (C). Average value (AVG), standard deviation (STD) and statistical significance of the difference between the test and the control samples (A-C and B-C, respectively) and between the two test samples (A-B), given by the respective probability (p). Statistically significant differences have also been evaluated for statistical power at α = 0.05 (P).