Table 2.
Clinical characteristics of patients according to the presence or absence of endothelial dysfunction
| Characteristics | Smokers | p | |
|---|---|---|---|
| ED + (n = 11) | ED − (n = 18) | ||
| Age, years (median, range) | 63 (44–77) | 62 (48–78) | 0.86 |
| Male:Female ratio | 7:4 | 16:2 | 0.11 |
| Tobacco, pack-years (mean, range) | 54 (30–120) | 46 (10–90) | 0.74 |
| Current smokers (n=) | 5 | 10 | 0.96 |
| FEV1, % predicted (mean, range) | 79 (67–101) | 92 (66–118) | 0.06 |
| OLD (n=) | 0 | 2 | 0.51 |
| GOLD 1 (n=) | 0 | 1 | 1 |
| GOLD 2 (n=) | 0 | 1 | 1 |
| Prior chemotherapy (n=) | 2 | 4 | 1 |
| Hypercholesterolemia (n=) | 2 | 1 | 0.53 |
| Hypertension (n=) | 2 | 5 | 0.68 |
| Diabetes mellitus (n=) | 1 | 3 | 1 |
| Treatment by statin (n=) | 1 | 5 | 0.36 |
| Vasodilating treatment (n=) | 1 | 3 | 1 |
ED+: endothelial dysfunction; ED−: no endothelial dysfunction; FEV1: forced expiratory volume in 1 second; OLD: presence of an obstructive pulmonary disease, defined as post-bronchodilator FEV1/forced vital capacity < 70%.