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Effects of BPE-CO2A, retinoic acid, and retinol on RAR mRNA expression in human fibroblasts (a) and RAR synthesis (brown precipitate) in human skin fragments labelled with anti-RXR antibodies (b) after a 48-hour incubation (40x magnification). The data represent the mean ± SD. ∗ P < 0.05, ∗∗ P < 0.01.
