Figure 4. SLBP is degraded by proteasome in G1.
HeLa cells were synchronized by double thymidine block method and treated with A) Cycloheximide alone (100 μM), B) Cycloheximide and Mg132 C) Mg132 alone for 1 hour at indicated cell cycle phases. Western blot analysis is performed using anti-SLBP serum. The cross-reacting band recognized by anti-SLBP serum serves as loading control. Cell cycle phases were confirmed by FACs analysis.