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Effects of fentanyl (25 µg/kg, i.v.) on body temperatures (arithmetic change) in conscious rats pretreated with vehicle (saline), naloxone methiodide (NLXmi; 1.5 or 5.0 mg/kg, i.v.) or naloxone (NLX, 1.5 mg/kg, i.v.). The data are presented as mean ± SEM. There were 6 rats in each group. *P < 0.05, significant change from post-drug value. †P < 0.05, NLXmi or NLX versus vehicle.
