Table 3.

Baseline values in study groups prior to injection of vehicle, naloxone or naloxone methiodide

	Naloxone Study		Naloxone methiodide Study
Parameter	Vehicle	NLX	Vehicle	NLXmi
Frequency (breaths/min)	124 ± 13	112 ± 10	122 ± 17	94 ± 11
Tidal Volume (mls)	2.11 ± 0.19	2.29 ± 0.14	2.29 ± 0.13	2.45 ± 0.12
Minute Ventilation (mls/min)	246 ± 23	252 ± 27	274 ± 31	235 ± 34
Inspiratory Time (sec)	0.17 ± 0.01	0.18 ± 0.01	0.17 ± 0.01	0.21 ± 0.03
Expiratory Time (sec)	0.37 ± 0.04	0.40 ± 0.04	0.37 ± 0.05	0.46 ± 0.05
End Inspiratory Pause (msec)	6.9 ± 0.4	7.6 ± 0.5	8.7 ± 0.7	8.6 ± 0.5
Peak Inspiratory Flow (mls/sec)	19.1 ± 1.7	19.9 ± 1.5	21.7 ± 1.9	19.7 ± 3.1
Peak Expiratory Flow (mls/sec)	14.0 ± 1.0	13.0 ± 0.8	13.4 ± 1.2	11.8 ± 1.4

Data are shown as mean ± SEM. NLX, naloxone. NLXmi, naloxone methiodide. There were 6 rats in each group. There were no significant between-group differences for any parameter (P > 0.05, for all comparisons).