Table 4.
Variables | Univariate regression | Adjusted multivariate regression | ||
---|---|---|---|---|
Odds ratio | P value | Odds ratio | P value | |
Age | 1.04 (1.01-1.07) | 0.006 | 1.02 (0.98-1.05) | 0.374 |
Gender | 0.82 (0.34-1.96) | 0.649 | 0.72 (0.21-2.45) | 0.597 |
APACHE II score | 1.20 (1.11-1.29) | <0.001 | 1.18 (1.08-1.29) | <0.001 |
Acute kidney injury | 2.90 (1.14-7.42) | 0.026 | 0.87 (0.19-4.05) | 0.863 |
Acute heart failure | 2.82 (1.06-7.51) | 0.039 | 1.84 (0.44-7.81) | 0.405 |
Severe sepsis | 3.62 (1.33-9.84) | 0.012 | 3.83 (0.74-19.74) | 0.109 |
Mechanical ventilation | 4.50 (1.76-11.47) | 0.002 | 3.05 (0.86-10.88) | 0.086 |
Chronic renal failure | 0.79 (0.17-3.74) | 0.764 | 1.04 (0.06-19.44) | 0.981 |
Chronic heart failure | 3.38 (0.34-33.76) | 0.300 | 4.66 (0.15-143.72) | 0.379 |
Overhydration at day 1 | 3.60 (1.44-8.98) | 0.006 | - | - |
High NT-ProBNP at day 1 | 2.54 (1.02-6.35) | 0.046 | - | - |
Overhydration + high NT-ProBNP at day 1 | 3.88 (1.61-9.36) | 0.002 | 1.02 (0.30-3.38) | 0.997 |
Variables in the multivariate regression included age, gender, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, acute kidney injury, acute heart failure, severe sepsis, mechanical ventilation, chronic renal failure, chronic heart failure, and presence of overhydration plus high N-terminal pro-B-type natriuretic peptide (NT-ProBNP) level.