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. 2015 Apr 2;19(1):135. doi: 10.1186/s13054-015-0871-3

Table 4.

Results of logistic regression analysis of risk factors for death (n = 89)

Variables Univariate regression Adjusted multivariate regression
Odds ratio P value Odds ratio P value
Age 1.04 (1.01-1.07) 0.006 1.02 (0.98-1.05) 0.374
Gender 0.82 (0.34-1.96) 0.649 0.72 (0.21-2.45) 0.597
APACHE II score 1.20 (1.11-1.29) <0.001 1.18 (1.08-1.29) <0.001
Acute kidney injury 2.90 (1.14-7.42) 0.026 0.87 (0.19-4.05) 0.863
Acute heart failure 2.82 (1.06-7.51) 0.039 1.84 (0.44-7.81) 0.405
Severe sepsis 3.62 (1.33-9.84) 0.012 3.83 (0.74-19.74) 0.109
Mechanical ventilation 4.50 (1.76-11.47) 0.002 3.05 (0.86-10.88) 0.086
Chronic renal failure 0.79 (0.17-3.74) 0.764 1.04 (0.06-19.44) 0.981
Chronic heart failure 3.38 (0.34-33.76) 0.300 4.66 (0.15-143.72) 0.379
Overhydration at day 1 3.60 (1.44-8.98) 0.006 - -
High NT-ProBNP at day 1 2.54 (1.02-6.35) 0.046 - -
Overhydration + high NT-ProBNP at day 1 3.88 (1.61-9.36) 0.002 1.02 (0.30-3.38) 0.997

Variables in the multivariate regression included age, gender, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, acute kidney injury, acute heart failure, severe sepsis, mechanical ventilation, chronic renal failure, chronic heart failure, and presence of overhydration plus high N-terminal pro-B-type natriuretic peptide (NT-ProBNP) level.