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Effects of TMC on histological observation in APAP-treated mice. Nor, normal mice; Con, mice treated with APAP (800 mg/kg BW); TMC-L, 100 mg/kg of TMC; TMC-M, 250 mg/kg of TMC; TMC-H, 500 mg/kg of TMC; S, 100 mg/kg of silymarin. Liver sections were stained with hematoxyline-eosin (H&E, ×500). The hepatocytes were analyzed to determine necrosis, fatty change, hepatocyte ballooning, and inflammatory cells infiltration.
