Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 19;199(4):1065–1076. doi: 10.1534/genetics.115.174490

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 by the Genetics Society of America

PMC Copyright notice

The NuA4 complex genetically interacts with the DNA damage tolerance (DDT) pathway. (A) Schematic of the NuA4 complex. Esa1 and Yng2 are part of the smaller piccolo NuA4 complex that also includes Epl1 and Eaf6. The large NuA4 complex forms when Epl1 in piccolo interacts with Eaf1. (B) Cell survival was measured after transient exposure to increasing concentrations of MMS for 1 hr at 30° for wild type (JC470), esa1-L254P (JC2767), ubc13Δ (JC2291), esa1-L254P/ubc13Δ (JC2775), rev3Δ (JC2289), and esa1-L254P/rev3Δ (JC2771), (C) yng2Δ (JC2036), yng2Δ/ubc13Δ (JC2285) and yng2Δ/rev3Δ (JC2281), or (D) rad51Δ (JC1362), esa1-L254P/rad51Δ (JC3253) and yng2Δ/rad51Δ (JC2437). Multiple experiments (three or more) were averaged with standard deviation being reported.