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. 2015 Mar 18;17(1):41. doi: 10.1186/s13058-015-0543-x

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© Yardley et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Distribution of quantitative total HER2 expression (H2T) in routine HER2 tests. HERmark equivocal (Eqv.) zone is defined within the two green vertical lines. Short vertical red line indicates the median of a H2T distribution. FISH, fluorescence in situ hybridization; HER2, human epidermal growth factor receptor 2; H2T, quantitative total HER2 expression by HERmark; IHC, immunohistochemistry.