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ATF4 increases the expression of M-CSF in breast cancer cells. (a) The mRNA level of M-CSF was increased in ATF4-overexpressing breast cancer cells. (b) The protein level of M-CSF was increased in ATF4-overexpressing breast cancer cells. (c) Immunohistochemical staining showed increased M-CSF level in ATF4-overexpressing breast cancer tissues.
