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. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Cell Rep. 2012 Sep 20;2(3):488–496. doi: 10.1016/j.celrep.2012.08.022

Figure 2. Inflammation Attenuates LTP in CA1 Region Only in WT Mice and This Can Be Prevented by Pharmacological Inhibition of α5GABAA Receptor.

Figure 2

(A) LPS impaired LTP induced by theta burst stimulation only in slices from WT mice. See also Figure S2.

(B) Summarized data showing the last 5 min of the recording. Note that pharmacological inhibition of α5GABAA receptors with L-655,708 prevented the impairment of LTP by LPS. Perfusion of the slices with L-655,708 (20 nM) was started 10 min before the stimulation and was present for LTP recording. Data are represented as mean ± SEM.