Table 1.
List of tau species detected and antibody reagents used in the AlphaLISA immunoassays developed for this study
| Tau Species | Biotin-donor | Acceptor |
|---|---|---|
| Total tau | Tau12 | HT7 |
| Tau aggregates | HT7 | HT7 |
| p231 | HT7 | PHF6 |
| pT202/205 | HT7 | AT8 |
| Global p-tau | HT7 | anti-pThr |
| pT231 | HT7 | AT180 |
| pT181 | HT7 | AT270 |
| pS212/T214 | HT7 | AT100 |
| pS262 | HT7 | pS262 |
| pT396 | HT7 | PHF13 |
| pS400 | HT7 | pS400 |
| pS404 | HT7 | pS404 |
| pS409 | HT7 | pS409 |
| pS412 | HT7 | pS412 |
| Ac-Lys280 | HT7 | Anti-Ac-Lys280 |
| Ac-tau | HT7 | anti-acetyl-Lys |
| pY-tau | HT7 | anti-p-tyrosine |
| ub-tau | HT7 | anti-ubiquitin |
| nY29 tau | HT7 | anti-nY29 |
| CSF total tau | HT7 | BT2 |