Table 3.
Response to treatment according to TTF1-expression (n = 178)
| TTF1 + 150 (84.3%) | TTF1 –n = 28 (15.7%) | p-value | |
|---|---|---|---|
| CR | 8 (5.3%) | 4 (14.3%) | |
| PR | 105 (70.0%) | 16 (57.1%) | |
| SD | 22 (14.7%) | 0 | |
| PD | 15 (10.0%) | 8 (28.6%) | 0.003 |
| RR | 75.3% | 71.4% | 0.642 |
| DCR (overall) | 135 (90.0%) | 20 (71.4%) | 0.013 |
| DCR stage III | 56/58 (96.6%) | 10/10 (100%) | 0.726 |
| DCR stage IV | 79/92 (85.9%) | 10/18 (55.6%) | 0.006 |
Overall response rate (RR) is defined as the proportion of patients having at least a partial response according to RECIST1.0. Disease control rate (DCR) is defined as all patients with at least a stable disease according to RECIST1.0. (CR = complete response; PR = partial response; SD = stable disease; PD = progressive disease).