Table 3. Associated Risk Factors for Incident CKD (Stage 3–5) (n = 268) after five-year follow-up of 2,620 patients (Multivariable Cox Regression).
| Variables | aHR | HR 95% CI | p value |
|---|---|---|---|
| Age | |||
| <60 years | 1 | ||
| 60–74 years | 1.86 | 1.25–2.77 | 0.002 |
| >74 | 3.20 | 2.13–4.81 | <0.001 |
| Albuminuria | |||
| < 30 mg/g | 1 | ||
| 30–299 mg/g | 1.67 | 1.11–2.50 | 0.013 |
| ≥ 300 mg/g | 4.57 | 2.46–8.48 | <0.001 |
| Gender | |||
| Male | 1 | ||
| Female | 1.15 | 0.89–1.49 | 0.283 |
| History of prior Hypertension | |||
| No | 1 | ||
| Yes | 2.02 | 1.42–2.89 | <0.001 |
| Duration of Diabetes Mellitus | |||
| <10 years | 1 | ||
| ≥10 years | 1.46 | 1.14–1.88 | 0.003 |
| Myocardial infarction | |||
| No | 1 | ||
| Yes | 1.72 | 1.25–2.37 | 0.001 |
| Dyslipidemia | |||
| No | 1 | ||
| Yes | 1.68 | 1.30–2.17 | <0.001 |
| SBP | |||
| <130 mmHg | 1 | ||
| 130–149 mmHg | 1.22 | 0.91–1.64 | 0.184 |
| >149 mmHg | 1.52 | 1.02–2.24 | 0.037 |
aHR: Adjusted Hazard Ratio; CI: Confidence Interval; CKD: Chronic Kidney Disease; SBP: Systolic Blood Pressure.