Table 1.
Main demographic and clinical characteristics of the study population
| Subjects with CMA at diagnosis | Subjects outgrown CMA | Healthy subjects | |
|---|---|---|---|
| Group 1 | Group 2 | Group 3 | |
| N | 10 | 20 | 10 |
| Male, n (%) | 7 (70) | 13 (65) | 4 (40) |
| Age, m (SD) | 5.5 (0.7) | 16.9 (0.9) | 9 (4) |
| Body weight, kg (SD) | 7.385 (964.7) | 12.160 (720.9) | 8.075 (3193.5) |
| Spontaneous delivery, n (%) | 5 (50) | 5 (25) | 4 (40) |
| Breastfeeding, ≤8 weeks, n (%) | 10 (100) | 20 (100) | 10 (100) |
| Symptoms at the CMA onset | |||
| Gastrointestinal, n (%) | 4 (40) | 8 (40) | - |
| Cutaneous, n (%) | 8 (80) | 15 (75) | - |
| Respiratory, n (%) | 1 (10) | 6 (30) | - |
| Total serum IgE, kU/l (SD) | 260.6 (230.9) | 193.1 (209.5) | 0.2 (0.1) |
| nBos d 4, kUA/l (SD) | 6 (11.2) | 1.9 (3) | - |
| nBos d 5, kUA/l (SD) | 4.5 (7.1) | 2 (3) | - |
| nBos d 6, kUA/l (SD) | 5.4 (8.7) | 1.4 (2.5) | - |
| nBos d 8, kUA/l (SD) | 22.7 (39.2) | 0.9 (1.9) | - |
| Lactoferrin, kUA/l (SD) | 2 (6.1) | 0 | - |