Table 1. Summary of clinical data and A20 mutations, gene copy numbers and expression of the analysed MM patients.
| ID | Subtype | Cytogenetics | A20 sequence analysis | A20 gene copy number | A20 expression |
|---|---|---|---|---|---|
| MM1 | polymorphic | t11/14 | rs368271377 | reduced | low |
| MM2 | polymorphic | del17, del13 | normal | high | |
| MM3 | lymphocytic | t11/14 | normal | moderate | |
| MM4 | lymphocytic | n.a. | normal | high | |
| MM5 | plasmablastic | del13 | normal | n.d. | |
| MM6 | plasmablastic | normal | normal | high | |
| MM7 | polymorphic | normal | rs368271377 | normal | low |
| MM8 | lymphocytic | normal | normal | moderate | |
| MM9 | lymphocytic | t11/14 | normal | high | |
| MM10 | plasmablastic | del13 | normal | n.d. | |
| MM11 | polymorphic | hyperploid | normal | n.d. | |
| MM12 | lymphocytic | n.a. | normal | high | |
| MM13 | lymphocytic | n.a. | normal | moderate | |
| MM14 | polymorphic | n.a. | normal | high | |
| MM15 | plasmablastic | normal | normal | moderate | |
| MM16 | polymorphic | n.a. | normal | n.d. | |
| MM17 | polymorphic | n.a. | normal | high | |
| MM18 | plasmablastic | del13 | normal | moderate | |
| MM19 | lymphocytic | n.a. | normal | n.d. | |
| MM20 | polymorphic | n.a. | reduced | low | |
| MM21 | polymorphic | n.a. | normal | n.d. | |
| MM22 | polymorphic | trisomy11, del13 | reduced | low | |
| MM23 | lymphocytic | n.a. | normal | low | |
| MM24 | polymorphic | del13 | normal | moderate | |
| MM25 | lymphocytic | t11/14 | normal | low | |
| MM26 | polymorphic | n.a. | rs143002189 | normal | n.d. |
| MM27 | polymorphic | del13, monosomy14, trisomy9 | normal | low | |
| ID | Subtype | Cytogenetics | A20 sequence analysis | A20 gene copy number | A20 expression |
| MM28 | plasmablastic | n.a. | normal | n.d. | |
| MM29 | plasmablastic | del13 | normal | moderate | |
| MM30 | lymphocytic | n.a. | normal | high | |
| MM31 | lymphocytic | del13 | normal | high | |
| MM32 | polymorphic | normal | reduced | low | |
| MM33 | lymphocytic | n.a. | normal | low | |
| MM34 | polymorphic | n.a. | reduced | n.d. | |
| MM36 | polymorphic | del13, trisomy 4, trisomy 9 | normal | moderate | |
| MM37 | plasmablastic | n.a. | normal | n.d. | |
| MM38 | plasmablastic | del13 | normal | moderate | |
| MM40 | polymorphic | n.a. | normal | high | |
| MM41 | lymphocytic | normal | normal | high | |
| MM42 | lymphocytic | del13 | normal | high | |
| MM43 | polymorphic | del13 | reduced | low | |
| MM44 | lymphocytic | n.a. | n.d. | n.d. | |
| MM46 | polymorphic | n.a. | normal | moderate | |
| MM47 | polymorphic | del13, trisomy 9 | reduced | low | |
| MM48 | lymphocytic | n.a. | normal | high | |
| MM49 | lymphocytic | n.a. | normal | moderate |
n.a. denotes not available
n.d. denotes not done