Table 1. Estimating secondary structure and other structural parameters.
Pairs of variables for correlation | PDB i.d.s | ||||||||||
2b4sb & 2auha | 1ybib& 1ybia | 1ye3 & 1n8ka | 1ulka& 1ulkb | 1kx5a& 1kx5e | 1tpda& 5tim_ | 1ftja & 1fw0a | 1ewka& 1ewkb | 1bpxa& 1bpya | 1aonn& 1xck | ||
Number of protein sequences | |||||||||||
1275 | 1275 | 2851 | 1058 | 334 | 1112 | 2694 | 2561 | 692 | 1940 | ||
SSE frequency | |||||||||||
31/15 & 32/17 | 2/50 (9) & 2/47 (9) | 24/24 (6) & 24/24 (6) | 10/10 (12) & 6/10 (12) | 47/0 & 49/0 | 39/16 & 39/15 | 35/18 & 34/18 | 33/19 & 33/19 | 44/15 & 43/15 | 48/13 & 50/18 | ||
MW (kDa) | |||||||||||
33.2 | 32.8 | 39.8 | 13.7 | 15.3 | 26.7 | 28.8 | 50.6 | 37.1 | 55.2 | ||
CATH class | |||||||||||
3.30.200.20 | 2.80.10.50 | 3.40.50.720 | 3.30.60.10 | 1.10.20.10 | 3.20.20.70 | 3.40.190.10 | 3.40.50.2300 | 3.30.210.10 | 3.30.260.10 | ||
Figure numbers | |||||||||||
1–3 | A,B,C | D,E,F | G,H,I | J,K,L | M,N,O | P,Q,R | S,T,U | V,W,X | Y,Z,Ø | ||
ENT | VAR | 0.97 | 0.96 | 0.96 | 0.98 | 0.96 | 0.97 | 0.97 | 0.95 | 0.95 | 0.92 |
KOL | ENT | 0.88 | 0.25 | 0.95 | 0.89 | 0.93 | 0.93 | 0.77 | 0.68 | 0.80 | 0.74 |
KOL | VAR | 0.84 | 0.24 | 0.90 | 0.85 | 0.91 | 0.90 | 0.72 | 0.62 | 0.75 | 0.67 |
HST | KOL | 0.08 | 0.05 | 0.11 | 0.05 | 0.16 | 0.03 | 0.18 | 0.06 | 0.08 | 0.10 |
HSTD | KOL | 0.06 | 0.03 | 0.11 | 0.05 | 0.13 | 0.06 | 0.11 | 0.04 | 0.00 | 0.03 |
AREA | ENT | 0.46 | 0.15 | 0.14 | 0.23 | 0.33 | 0.45 | 0.10 | 0.10 | 0.38 | 0.31 |
VAR | 0.43 | 0.13 | 0.12 | 0.21 | 0.29 | 0.40 | 0.10 | 0.09 | 0.29 | 0.22 | |
KOL | 0.45 | 0.06 | 0.07 | 0.32 | 0.22 | 0.39 | 0.16 | 0.08 | 0.33 | 0.26 | |
BVLA | ENT | 0.26 | 0.16 | 0.16 | 0.08 | 0.44 | 0.26 | 0.31 | 0.21 | 0.23 | 0.32 |
VAR | 0.22 | 0.14 | 0.14 | 0.06 | 0.40 | 0.24 | 0.31 | 0.21 | 0.23 | 0.29 | |
KOL | 0.24 | 0.22 | 0.04 | 0.24 | 0.26 | 0.24 | 0.21 | 0.11 | 0.14 | 0.42 | |
BVLI | ENT | 0.33 | 0.02 | 0.22 | 0.09 | 0.47 | 0.26 | 0.43 | 0.29 | 0.28 | 0.29 |
VAR | 0.33 | 0.01 | 0.17 | 0.08 | 0.42 | 0.26 | 0.44 | 0.28 | 0.24 | 0.27 | |
KOL | 0.35 | 0.12 | 0.20 | 0.25 | 0.29 | 0.25 | 0.38 | 0.01 | 0.16 | 0.39 | |
OACA | ENT | 0.57 | 0.21 | 0.29 | 0.34 | 0.01 | 0.36 | 0.15 | 0.35 | 0.38 | 0.37 |
VAR | 0.55 | 0.16 | 0.27 | 0.34 | 0.23 | 0.35 | 0.16 | 0.34 | 0.38 | 0.32 | |
KOL | 0.49 | 0.05 | 0.24 | 0.18 | 0.07 | 0.33 | 0.09 | 0.11 | 0.28 | 0.27 | |
OACI | ENT | 0.58 | 0.21 | 0.28 | 0.35 | 0.07 | 0.34 | 0.18 | 0.37 | 0.35 | 0.33 |
VAR | 0.56 | 0.16 | 0.27 | 0.35 | 0.09 | 0.33 | 0.20 | 0.35 | 0.37 | 0.28 | |
KOL | 0.53 | 0.06 | 0.24 | 0.17 | 0.10 | 0.30 | 0.10 | 0.13 | 0.24 | 0.22 | |
DISP | ENT | 0.05 | 0.18 | 0.15 | 0.03 | 0.26 | 0.15 | 0.28 | 0.12 | 0.04 | 0.27 |
VAR | 0.05 | 0.14 | 0.13 | 0.04 | 0.25 | 0.12 | 0.31 | 0.12 | 0.03 | 0.24 | |
KOL | 0.09 | 0.03 | 0.19 | 0.02 | 0.16 | 0.17 | 0.12 | 0.22 | 0.02 | 0.41 | |
BVLC | ENT | 0.15 | 0.17 | 0.15 | 0.02 | 0.17 | 0.08 | 0.36 | 0.02 | 0.19 | 0.20 |
VAR | 0.12 | 0.15 | 0.12 | 0.02 | 0.18 | 0.05 | 0.37 | 0.03 | 0.15 | 0.20 | |
KOL | 0.13 | 0.32 | 0.22 | 0.01 | 0.01 | 0.06 | 0.36 | 0.22 | 0.10 | 0.28 |
Below the PDB I.d.s of the protein pairs studied are in order: the number of sequences in each alignment (as treated by the PredictProtein program), the relative frequency of secondary structures (%alpha-helix/%beta-strand) in each member of the protein pair (Note: for 1ulka/1ulkb, a 310-rich protein, and likewise 1ybib/1ybia and 1ye3/1n8ka the 310 content is added in parentheses), the molecular weight of the protein, the CATH class (SCOP classes are not as useful, since the SSE data already alludes to this kind of classification) and a key to the numbers of the corresponding figures. The correlation data for each protein (pair) for each type of analysis completes the table. For HST/HSTD, only data for KOL are shown.