Table 2. Grading of Recommendations, Assessment, and Evaluation (GRADE) ranking for evidence of two outcomes.
| No of studies | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Ortho-k | Control | Mean Difference | Quality | Importance |
|---|---|---|---|---|---|---|---|---|---|---|
| 7 studies 1 | Serious 3 | No serious inconsistency | No serious indirectness | No serious imprecision | None | 218 | 217 | 0.27 (CI: 0.32 to 0.22) | Moderate | Critical |
| 2 studies 2 | Serious 3 | No serious inconsistency | No serious indirectness | No serious imprecision | None | 63 | 63 | 0.22 (CI: 0.31 to 0.14) | Moderate | Critical |
1 Axial length (follow-up mean 2 years; better indicated by lower values).
2 Vitreous chamber length (follow-up mean 2 years; better indicated by lower values).
3 Most of studies did not use blinding method.