Table 4.
Absolute and relative changes in body composition, areal BMD, volumetric BMD, bone strength, bone markers, parathyroid hormone (PTH), 25-hydroxy (25-OH) vitamin D and aerobic power in the weight stable women (n=10).
| Baseline | 4 Months | Mean Change (95% CI) (% Change) | p value | |
|---|---|---|---|---|
| Body Composition (kg) | ||||
| Total Mass | 73.6±13.5 | 73.9±13.4 | 0.3(−1.0,1.7) (0.48 %) | 0.61 |
| Fat Mass | 29.2±8.9 | 29.7±9.0 | 0.4(−0.5,1.4) (1.63 %) | 0.33 |
| Fat Free Mass | 44.4±6.2 | 44.3±5.7 | −0.1(−0.9,0.6) (−0.14%) | 0.71 |
|
| ||||
| Areal BMD (g/cm2) | ||||
| Hip | 0.878±0.091 | 0.867±0.089 | −0.011(−0.024,0.002) (−1.23%) | 0.09 |
| Femoral Neck | 0.750±0.090 | 0.759±0.088 | 0.009(−0.006,0.024) (1.29 %) | 0.20 |
| Trochanter | 0.661±0.104 | 0.652±0.100 | −0.009(−0.023,0.005) (−1.25%) | 0.19 |
| Subtrochanter | 1.044±0.113 | 1.032±0.125 | −0.012(−0.028,0.003) (−1.30%) | 0.10 |
|
| ||||
| Volumetric BMD (g/cm3) | ||||
| Total Hip | 281.8±33.6 | 273.5±40.9 | −8.3(−24.0,7.4) (−3.00%) | 0.26 |
| Cortical | 881.6±76.6 | 855.8±45.6 | −25.8(−73.4,21.7) (−2.50%) | 0.25 |
| Trabecular | 130.2±15.8 | 126.7±16.2 | −3.5(−11.1,4.1) (−2.47%) | 0.33 |
| Total Neck | 295.1±42.2 | 285.5±49.8 | −9.6(−29.3,10.2) (−3.28%) | 0.30 |
| Cortical | 904.3±105.0 | 899.8±106.5 | −4.5(−62.6,53.6) (−0.12%) | 0.86 |
| Trabecular | 134.4±13.0 | 132.7±15.9 | −1.7(−8.3,5.0) (−1.25%) | 0.58 |
|
| ||||
| Bone Strength (Femoral Neck) | ||||
| CSMImax (mgxcm) | 1935±678 | 3279±3305 | 1345(−832.8,3522.2) (57.89%) | 0.20 |
| SMmax (cm3) | 4.8±1.4 | 7.0±4.4 | 2.2(−0.4,4.8) (40.01%) | 0.08 |
| CSMImin (mgxcm) | 1532±550 | 1830±1063 | 298(−175.7,772.0) (15.33%) | 0.19 |
| SMmin (cm3) | 4.3±1.2 | 5.4±2.4 | 1.1(−0.4,2.5) (24.57%) | 0.13 |
|
| ||||
| Bone Markers | ||||
| CTX (ng/mL) | 0.6±0.2 | 0.7±0.3 | 0.1(−0.0,0.2) (17.90%) | 0.15 |
| BAP (U/L) | 30.8±7.5 | 30.5±6.3 | −0.3(−4.4,3.8) (1.38 %) | 0.87 |
|
| ||||
| PTH (pg/mL) | 50.6±28.0 | 58.6±28.0 | 8.0(−3.5,19.5) (21.51%) | 0.15 |
|
| ||||
| Vitamin D (25OH) (ng/mL) | 29.4±6.7 | 30.7±6.1 | 1.3(−3.4,6.0) (7.73%) | 0.54 |
P values are based on a paired t test.
BMD: bone mineral density; CSMImax: cross-sectional moment of inertia, strong axis of bone; CSMImin: cross-sectional moment of inertia, weak axis of bone; Zmax: section modulus, strong axis of bone; Zmin: section modulus, weak axis of bone.