Table 1. Participant characteristics by quartiles of complement C3 (n = 2,733) a .
| Quartiles of complement C3 (g/L, range) | |||||
|---|---|---|---|---|---|
| Level 1 (0.53–0.89) | Level 2 (0.90–1.02) | Level 3 (1.03–1.13) | Level 4 (1.14–1.93) | p for trend b | |
| (n = 689) | (n = 734) | (n = 590) | (n = 720) | ||
| Age (y) | 47.6 (46.8, 48.3) c | 49.1 (48.3, 49.8) | 50.6 (49.7, 51.4) | 49.2 (48.4, 49.9) | <0.0001 |
| Sex (males, %) | 48.9 | 62.4 | 61.9 | 60.7 | <0.0001 |
| BMI (kg/m2) | 23.4 (23.2, 23.6) | 25.1 (24.8, 25.3) | 25.7 (25.5, 26) | 27.1 (26.9, 27.4) | <0.0001 |
| Waist circumference (cm) | 79.0 (78.3, 79.7) | 84.9 (84.2, 85.7) | 86.7 (85.9, 87.5) | 90.6 (89.9, 91.4) | <0.0001 |
| TC (mmol/L) | 4.63 (4.57, 4.7) | 4.85 (4.79, 4.92) | 4.97 (4.9, 5.05) | 5.20 (5.13, 5.27) | <0.0001 |
| TG (mmol/L) | 0.98 (0.95, 1.02) | 1.34 (1.29, 1.39) | 1.46 (1.40, 1.52) | 1.77 (1.71, 1.84) | <0.0001 |
| LDL (mmol/L) | 2.54 (2.48, 2.59) | 2.80 (2.74, 2.86) | 2.90 (2.83, 2.97) | 3.05 (2.98, 3.11) | <0.0001 |
| HDL (mmol/L) | 1.52 (1.50, 1.55) | 1.32 (1.30, 1.35) | 1.29 (1.27, 1.32) | 1.24 (1.22, 1.26) | <0.0001 |
| SBP (mmHg) | 118.4 (117.2, 119.6) | 122.5 (121.4, 123.7) | 126.2 (124.9, 127.6) | 128.8 (127.5, 130.1) | <0.0001 |
| DBP (mmHg) | 74.5 (73.7, 75.3) | 77.5 (76.7, 78.3) | 79.7 (78.7, 80.6) | 82.2 (81.3, 83.1) | <0.0001 |
| FBS (mmol/L) | 5.04 (4.98, 5.10) | 5.25 (5.19, 5.31) | 5.39 (5.32, 5.46) | 5.52 (5.46, 5.58) | <0.0001 |
| ALT(mmol/L) | 14.2 (13.7, 14.8) | 17.8 (17.2, 18.5) | 20 (19.2, 20.9) | 24.3 (23.4, 25.2) | <0.0001 |
| AST(mmol/L) | 17.1 (16.7, 17.5) | 18.2 (17.8, 18.6) | 19.0 (18.6, 19.5) | 20.7 (20.2, 21.2) | <0.0001 |
| GGT(mmol/L) | 17.5 (16.7, 18.4) | 22.9 (21.9, 24.0) | 26.1 (24.8, 27.4) | 32.4 (31.0, 33.9) | <0.0001 |
| Smoking status (%) | |||||
| Smoker | 23.1 | 31.3 | 30.3 | 28.1 | 0.09 |
| Ex-smoker | 0.15 | 0.00 | 0.00 | 0.00 | 0.92 |
| Nonsmoker | 76.5 | 68.7 | 69.5 | 71.8 | 0.04 |
| Drinker (%) | 40.4 | 43.6 | 44.9 | 44.9 | 0.08 |
| Family history of diseases (%) | |||||
| CVD | 28.3 | 32.6 | 30.2 | 30.1 | 0.68 |
| Hypertension | 40.6 | 39.5 | 42.4 | 41.2 | 0.59 |
| Hyperlipidemia | 0.00 | 0.14 | 0.00 | 0.00 | 0.66 |
| Diabetes | 18.3 | 16.4 | 21.0 | 20.6 | 0.09 |
a BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein cholesterol; HDL, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transpeptidase; CVD, cardiovascular disease.
b Analysis of variance or logistic regression analysis.
c Geometric mean (95% confidence interval) (all such values).