Table 2. Participant characteristics by quartiles of complement 3 in males (n = 978) a .
| Quartiles of complement 3 (g/L, range) | |||||
|---|---|---|---|---|---|
| Level 1 (0.54–0.88) | Level 2 (0.88–0.98) | Level 3 (0.99–1.09) | Level 4 (1.11–1.93) | p for trend b | |
| (n = 245) | (n = 246) | (n = 234) | (n = 253) | ||
| Age (y) | 50.1 (48.8, 51.5) c | 50.2 (48.9, 51.6) | 49.0 (47.7, 50.4) | 46.9 (45.7, 48.2) | 0.25 |
| BMI (kg/m2) | 24.0 (23.7, 24.4) | 24.9 (24.5, 25.2) | 25.6 (25.2, 25.9) | 26.6 (26.2, 26.9) | <0.0001 |
| Waist circumference (cm) | 84.4 (83.4, 85.4) | 87.4 (86.4, 88.4) | 89.4 (88.3, 90.4) | 92.3 (91.2, 93.4) | <0.0001 |
| TC (mmol/L) | 4.60 (4.50, 4.70) | 4.87 (4.76, 4.98) | 4.92 (4.81, 5.03) | 5.12 (5.01, 5.23) | <0.0001 |
| TG (mmol/L) | 1.12 (1.05, 1.19) | 1.35 (1.27, 1.44) | 1.51 (1.41, 1.61) | 1.72 (1.62, 1.83) | <0.0001 |
| LDL (mmol/L) | 2.59 (2.50, 2.68) | 2.81 (2.72, 2.91) | 2.87 (2.77, 2.98) | 3.01 (2.91, 3.12) | <0.0001 |
| HDL (mmol/L) | 1.39 (1.35, 1.44) | 1.32 (1.28, 1.36) | 1.25 (1.22, 1.29) | 1.24 (1.21, 1.28) | <0.0001 |
| SBP (mmHg) | 122.1 (120.1, 124.1) | 124.6 (122.6, 126.7) | 126.1 (124, 128.2) | 126.8 (124.8, 128.9) | <0.01 |
| DBP (mmHg) | 78.1 (76.7, 79.5) | 79.8 (78.4, 81.3) | 80.8 (79.4, 82.4) | 83.2 (81.7, 84.6) | <0.01 |
| FBS (mmol/L) | 5.14 (5.04, 5.24) | 5.28 (5.18, 5.39) | 5.33 (5.23, 5.44) | 5.44 (5.34, 5.55) | <0.01 |
| ALT(mmol/L) | 15.8 (14.9, 16.7) | 18.7 (17.6, 19.8) | 20.4 (19.2, 21.7) | 24.3 (23.0, 25.8) | <0.0001 |
| AST(mmol/L) | 17.3 (16.6, 17.9) | 18.5 (17.8, 19.3) | 18.7 (18.0, 19.5) | 20.4 (19.6, 21.2) | <0.01 |
| GGT(mmol/L) | 23.5 (21.8, 25.4) | 27.6 (25.6, 29.8) | 30.7 (28.4, 33.2) | 40.3 (37.4, 43.4) | <0.0001 |
| Smoking status (%) | |||||
| Current smoker | 47.8 | 48.8 | 46.2 | 44.7 | 0.40 |
| Ex-smoker | 0.41 | 0.00 | 0.00 | 0.00 | - |
| Nonsmoker | 51.4 | 51.2 | 53.8 | 55.3 | 0.37 |
| Drinker (%) | 65.3 | 65.0 | 67.5 | 80.6 | <0.001 |
| Family history of diseases (%) | |||||
| CVD | 24.1 | 34.2 | 29.5 | 31.2 | 0.19 |
| Hypertension | 38.4 | 41.5 | 39.3 | 43.5 | 0.34 |
| Hyperlipidemia | 0.00 | 0.00 | 0.00 | 0.00 | - |
| Diabetes | 15.9 | 13.0 | 17.1 | 19.8 | 0.14 |
a BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein cholesterol; HDL, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBS, fasting blood sugar; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transpeptidase; CVD, cardiovascular disease.
b Analysis of variance or logistic regression analysis.
c Geometric mean (95% confidence interval) (all such values).