Table 4. Adjusted odds ratios of quartiles of complement 3 to AFLD in males (n = 978) a .
| Quartiles of complement 3 (g/L, range) | |||||
|---|---|---|---|---|---|
| Level 1 (0.54–0.88) | Level 2 (0.88–0.98) | Level 3 (0.99–1.09) | Level 4 (1.11–1.93) | p for trend b | |
| (n = 245) | (n = 246) | (n = 234) | (n = 253) | ||
| No. of AFLD | 16 | 34 | 58 | 78 | - |
| Model 1 d | 1.00 | 2.30 (1.25, 4.38) c | 4.72 (2.68, 8.74) | 6.38 (3.69, 11.68) | <0.0001 |
| Model 2 e | 1.00 | 1.88 (0.98, 3.72) | 3.41 (1.86, 6.54) | 3.10 (1.69, 5.94) | <0.0001 |
| Model 3 f | 1.00 | 1.72 (0.86, 3.53) | 2.95 (1.54, 5.90) | 2.09 (1.08, 4.18) | 0.02 |
a AFLD, alcoholic fatty liver disease; BMI, body mass index.
b Multiple logistic regression analysis.
c Adjusted odds ratios (95% confidence interval) (all such values).
d Crude model.
e Adjusted for log-transformed age, sex and log-transformed BMI.
f Additionally adjusted for smoking status, drinking status, and family history of cardiovascular disease, hypertension, diabetes and log-transformed ALT, AST and GGT.