Fig 4. Effect of T. gondii infection on body weight is shown in female and male Nurr1 +/+ and +/- mice as percent change in body weight from weight prior to infection to body weight 6 weeks after infection or vehicle injection (Control).

Infection with T. gondii significantly reduced weight gain (A.). There was no significant interaction in the change in body weight due to either the genotype or sex, however, the +/- mice gained less weight over this time (B., C.) and the infected male mice, on average, lost weight (C.) while the infected female mice showed no change in body weight (B.). #significant difference due to treatment based on ANOVA with Fischer’s post hoc comparison. n = 10 female +/+ controls; 9 female +/- controls; 5 female +/+ T. gondii; 10 female +/- T. gondii; 18 male +/+ control; 11 male +/- controls; 9 male +/+ T. gondii; 8 male +/- T. gondii.