Table 2.
Base annual malaria incidence, annual incidence averted/1000 c and annual disability-adjusted life-years saved/1000 people.
| Low HIV prevalence | Intermediate HIV prevalence | High HIV prevalence | |
|---|---|---|---|
| EIR of 10 (base annual incidence) | 2.43 (95% CI 0.05–4.49) | 2.54 (95% CI 0.05–4.50) | 2.63 (95% CI 0.06–4.74) |
| EIR of 10 (annual incidence averted/1000 people) | 0.03a (95% CI 0.01–0.10) | 5.2 (95% CI 1.90–11.2) | 25.5 (95% CI 8.70–50.2) |
| EIR of 10 (annual DALYs saved/1000 people) | 0.002 (95% CI 0.001–0.004) | 0.22 (95% CI 0.10–0.56) | 1.04 (95% CI 0.48–2.7) |
| EIR of 112 (base annual incidence) | 4.87 (95% CI 2.82–6.94) | 4.88 (95% CI 2.82–6.94) | 4.88 (95% CI 3.10–6.75) |
| EIR of 112 (annual incidence averted/1000 people) | 0.08 (95% CI 0.04–0.15) | 10.3 (95% CI 6.97–16.46) | 51.8 (95% CI 37.1–76.7) |
| EIR of 112 (annual DALYs saved/1000 people) | 0.004 (95% CI 0.002–0.008) | 0.55 (95% CI 0.24–0.99) | 2.82 (95% CI 1.14–5.12) |
| EIR of 562 (base annual incidence) | 6.00 (95% CI 4.44–8.85) | 6.02 (95% CI 4.44–8.61) | 6.03 (95% CI 4.51–8.77) |
| EIR of 562 (annual incidence averted/1000 people) | 0.10 (95% CI 0.05–0.2) | 13.0 (95% CI 9.09–22.6) | 65.8 (95% CI 47.0–106.2) |
| EIR of 562 (annual DALYs saved/1000 people) | 0.006 (95% CI 0.003–0.01) | 0.8 (95% CI 0.4–1.6) | 4.3 (95% CI 1.70–7.91) |
CI, confidence interval; DALYs, disability-adjusted life-years; EIR, entomological inoculation rate.
a
Failure to reject the hypothesis that the population median is less than the sample median at the α = 0.05 significance level through the Wilcoxon signed-rank test. Base annual incidence corresponds to 100% NNRTI HIV treatment. Model represents incidence and DALYs for all children, both HIV-infected and HIV-uninfected.