Table 3. Multivariate analysis on major traditional pathological parameters by Ki67 grade or Ki67/CK grade.

Parameters	Analysis by Ki67 grade		Analysis by Ki67/CK grade
	HR (95%CI)	P value	HR (95%CI)	P value
T stage	1.194 (0.814–1.750)	0.365	1.223 (0.835–1.789)	0.301
N stage	1.753 (1.446–2. 125)	< 0.001	1.819 (1.501–2.204)	< 0.001
Histological grade	2.958 (1.957–4.472)	< 0.001	2.894 (1.924–4.352)	< 0.001
ER status	0.900 (0. 617–1.312)	0.584	0.902 (0.622–1.308)	0.587
HER2 gene	1.553 (0.957–2.522)	0.075	1.748 (1.087–2.812)	0.021
Ki67 grade	1.773 (1.009–3.117)	0.047	ND
Ki67/CK grade	ND		2.019 (1.254–3.251)	0.004

ND: not done.