Skip to main content
. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Leukemia. 2014 Nov 3;29(4):939–946. doi: 10.1038/leu.2014.310

Figure 3. IL-35 promoted regulatory T cell expansion.

Figure 3

The percentages of (A) CD4+FoxP3+T cells and (B) CD8+FoxP3+T cells on gated CD4+ T cells in the spleen, liver, lung and small intestine of recipients administrated with HGT/IL-35, HGT/control, HGT/IL-35+anti-IL-35 and HGT/IL-35+IgG control were shown. In vivo CD4+ (C), CD8+ (D), CD4+FoxP3+ (E), and CD8+FoxP3+ (F) T-cell proliferations were assessed via BrdU incorporation after 4 h in vivo BrdU pulse in the spleen, lung, liver and small intestine of recipients. Values were expressed as Mean±SEM. All the experiments were performed with eight mice per group. The data shown are the representative of three experiments. *p<0.05, **p<0.01.