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. 2015 Mar 8;6(5):448–456. doi: 10.7150/jca.11400

Figure 3.

Figure 3

A combination of anti-gastrins antiserum and cytotoxic drugs (5-FU + CDDP) treatment assessed on the growth curve (A), the final median volume (B), the final median weight (C) of SGC-7901 tumors. (a) diamond, N.C. (◇ negative control), normal rabbit serum (200 mg/kg/2 days, i.p.) treated; square, H.C. (☐ standard high-dose chemotherapeutic combination), 5-FU (50 mg/kg/10 days, i.p.) combined with CDDP (5 mg/kg/10 days, i.p.) treated; triangle, combined H (Δ combined high dose), antiserum (200 mg/kg/2 days, i.p.) combined with lowered (40% reduced) 5-FU (20 mg/kg/7 days, i.p.) and CDDP (2 mg/kg/7 days, i.p.) treated; cross, combined M (× combined medium dose), antiserum (150 mg/kg/2 days, i.p.) combined with 5-FU (20 mg/kg/7 days, i.p.) and CDDP (2 mg/kg/7 days, i.p.) treated; crossed star, combined L (* combined low dose), antiserum (100 mg/kg/2 days, i.p.) combined with 5-FU (20 mg/kg/7 days, i.p.) and CDDP (2 mg/kg/7 days, i.p.) treated; circle, S.A. (○ single antiserum), antiserum (200 mg/kg/2 days, i.p.) treated; line, S.C. (+ single chemical), 40% reduced 5-FU (20 mg/kg/7 days, i.p.) combined with 40% reduced CDDP (2 mg/kg/7 days, i.p.) treated. Experimental groups consisted of 8 animals. The data were analyzed between groups using Student's t test. Statistical significance: *p < 0.05 vs N.C.