Fig. 3.

Immunostaining. a, b Myxoid liposarcoma with lipoma-like change (MLSLC) shows negative staining for CDK4 and MDM2. c, d Well-differentiated liposarcoma exhibit nuclear expressions of CDK4 and MDM2. e, f MLSLC shows positive nuclear staining for PPARγ and C/EBPα. g Adipophilin is strongly positive in immature lipoblastic cells of MLSLC. h Perilipin is positive in large fat vacuoles of mature adipocytes and multivacuolated lipoblasts of MLSLC. i, j The Ki-67 index is very low in i the lipoma-like area of MLSLC, when compared with j the myxoid area of the same tumor