TABLE 2:

Categories of adverse events

Category of adverse event	Mavacoxib Case number	Clinical severity of event	ABON* classification	Carprofen Case number	Clinical severity of event	ABON* classification
Digestive tract disorders	F0206	Minor, transient	B	F0201	Fatal	A
	F0212	Minor, transient	N	F0205	Minor, transient	B
	F0216	Minor, transient	B	F0209	Fatal	B
	F0401	Minor, transient	B	F0404	Minor, transient	B
	F0804	Minor, transient	N	F1013	Minor, transient	B
	F1003	Minor, transient	N
	F1108	Minor, transient	B
	F1201	Minor, transient, occurred twice	B
	F1205	Minor, transient	B
	F1206	Minor, transient	B
Skin and appendages disorders	F0204	Minor, transient	N	F0205	Minor, long-term	N
	F0216	Minor, transient	N	F0405	Minor, transient	N
	F0218	Minor, transient	N	F0509	Minor, transient	N
	F0305	Minor, transient	N	F0606	Minor, long-term	N
	F0310	Minor, transient	N	F0702	Minor, transient	N
	F0311	Minor, transient	N	F0801	Minor, transient	N
	F0504	Minor, transient	N	F0814	Minor, transient	N
	F0906	Minor, transient	N	F0907	Minor, transient	N
	F1009	Minor, transient	N	F1011	Minor, transient	N
Neurological disorders	F0302	Minor, transient	N	F0205	Significant, long-term	N
	F0304	Significant, transient	N	F0910	Serious, long-term	N
	F0508	Significant, transient	N
Respiratory tract disorders	F0108	Serious/critical	N	F0107	Significant, transient	N
	F0408	Minor, transient	N	F0219	Serious, long-term	N
Reproductive system disorders	F0402	Significant, recurrent	N	F0207	Minor, transient	N
				F1001	Significant, recurrent	N
Musculoskeletal disorders	F0102	Significant, possibly long-term	N	F0205	Significant, possibly recurrent	N
				F0512	Significant, transient	N
Renal and urinary disorders	F0308	Serious, long-term	N
Systemic disorders	F0401	Fatal	B	F0403	Serious/critical	N
				F0501	Minor, transient	N
				F0903	Significant, possibly recurrent	N
Eye disorders				F0201	Significant, possibly long-term	N
Hepatobiliary disorders				F1107	Serious/critical	N
Behavioural disorders				F1111	Minor/transient	N

*ABON classification of causality: A=Probable; B=Possible; O=Unclassifiable/unassessable; N=Unlikely