TABLE 5:
Clinical pathology variables
| |
Screening |
Day 134 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Ref. range | Treatment | Mean | sd | Median | Min./max. | Mean | sd | Median | Min./max. |
| Erythrocyte count (mm³) | 5.5–8.5 | Mavacoxib | 6.5 | 0.91 | 6.53 | 3.8/9.66 | 6.8 | 1.09 | 6.63 | 4.49/10.67 |
| Carprofen | 6.5 | 0.78 | 6.5 | 4.16/8.27 | 7.0 | 0.92 | 6.96 | 4.90/10.36 | ||
| Haematocrit (%) | 37–55 | Mavacoxib | 46.4 | 6.2 | 45.3 | 28.1/62.6 | 49.1 | 7.5 | 49.8 | 34.4/79 |
| Carprofen | 46.6 | 5.7 | 46.7 | 31.6/57.6 | 51.4 | 7.5 | 51.0 | 36.9/79.9 | ||
| Albumin (g/L) | 20–40 | Mavacoxib | 30 | 3 | 30 | 21/37 | 31 | 3 | 31 | 25/39 |
| Carprofen | 30 | 3 | 31 | 24/38 | 31 | 3 | 32 | 24/44 | ||
| Urea (g/L) | 0.15–0.5 | Mavacoxib | 0.4 | 0.15 | 0.35 | 0.15/0.95 | 0.5 | 0.2 | 0.46 | 0.23/1.19 |
| Carprofen | 0.4 | 0.14 | 0.32 | 0.15/0.91 | 0.4 | 0.17 | 0.37 | 0.15/1.12 | ||
| Creatinine (mg/L) | 0–15 | Mavacoxib | 8.5 | 2.2 | 8.0 | 5.0/15.0 | 9.5 | 2.9 | 9.0 | 4.0/22.0 |
| Carprofen | 8.4 | 2.1 | 8.0 | 5.0/16.0 | 9.2 | 2.4 | 9.0 | 5.0/16.0 | ||