Table 1.
Track description for BRCA1 Circos
| Track number | Description |
|---|---|
| Track 1 | Exon number |
| Track 2 | BIC entries (BIC; August 2012)—http://research.nhgri.nih.gov/bic/ |
| Track 3 | IARC class16 |
| Track 4 | Computational classification of transcriptional assay data20 |
| Track 5 | Bayes’ factor20 |
| Track 6 | Exome viewer—http://evs.gs.washington.edu/EVS/ |
| Track 7 | Reference amino acid |
| Track 8 | Codon |
| Track 9 | Variant amino acid |
| Track 10 | Align-GVGD (http://brca.iarc.fr/PRIORS/BRCA1/index.php) |
| Track 11 | BARD binding22 |
| Track 12 | E2 binding22 |
| Track 13 | Ubiquitin ligase activity22 |
| Track 14 | Ubiquitin ligase activity24 |
| Track 15 | Bimolecular fluorescence complementation25 |
| Track 16 | Protease sensitivity26 |
| Track 17 | Phosphopeptide-binding activity26 |
| Track 18 | Phosphopeptide-binding specificity26 |
| Track 19 | Transcription assay26 |
| Track 20 | Transcription assay27 |
| Track 21 | Transcription assay17 |
| Track 22 | Transcription assay13 |
| Track 23 | Transcription assay28 |
| Track 24 | Transcription assay29 |
| Track 25 | Transcription assay30 |
| Track 26 | Transcription assay31 |
| Track 27 | Transcription assay32 |
| Track 28 | Transcription assay33 |
| Track 29 | Transcription assay34 |
| Track 30 | Transcription assay35 |
| Track 31 | Transcription assay36 |
| Track 32 | Transcription assay37 |
| Track 33 | Small colony phenotype38 |
| Track 34 | Small colony phenotype39 |
| Track 35 | Small colony phenotype40 |
| Track 36 | Small colony phenotype41 |
| Track 37 | Yeast localisation phenotype41 |
| Track 38 | ES viability42 |
| Track 39 | ES viability43 |
| Track 40 | Restoration of radiation resistance44 |
| Track 41 | Increase/restoration in radiation resistance24 |
| Track 42 | Homology-directed repair45 |
| Track 43 | Homology-directed repair46 |
| Track 44 | Homology-directed repair43 |
| Track 45 | Single-strand annealing46 |
| Track 46 | Centrosome number47 |
| Track 47 | Yeast intrachromosomal recombination40 |
| Track 48 | Yeast interchromosomal recombination40 |
| Track 49 | G2/M checkpoint proficiency24 |
| Track 50 | Subcellular localisation/formation of foci after IR48 |
| Track 51 | Subcellular localisation/cytoplasmic mislocalisation49 |
| Track 52 | Cisplatin response43 |
| Track 53 | PARP inhibitor sensitivity43 |
BIC, Breast Cancer Information Core; ES, Embryonic Stem Cell; GVGD, Grantham Variation-Grantham Deviation; IR, ionizing radiation; IARC, International Agency for Research on Cancer; PARP, Poly ADP Ribose Polymerase.