Table 4.

An optimised logistic regression model (incorporating HLA Class I, IFNL3 and KIR) predicting viral clearance

Explanatory Variables	OR (95% CIs)	p Value
A*03	0.42 (0.23 to 0.76)	0.005
B*15	0.12 (0.03 to 0.52)	0.004
C*01	0.13 (0.03 to 0.5)	0.003
C*09	10.74 (1.42 to 81.3)	0.022
C*12	0.31 (0.11 to 0.86)	0.024
IFNL3 CC versus CT/TT	0.11 (0.06 to 0.19)	<0.001
KIR2DS3	3.45 (1.77 to 6.72)	<0.001

The explanatory variables are selected by forward and reverse stepwise selection minimising Akaike Information Criteria. OR, CIs and p values are presented. The dataset consists of patients from the Irish cohort who have had their HLA Class I genotype determined (n=319).

IFNL3 CC, protective genotype; IFNL3 CT/TT, deleterious genotype.