. 2015 Jan 22;290(15):9542–9554. doi: 10.1074/jbc.M114.596098

TABLE 4.

Bias factors at CCR5

The bias factors were calculated as described under “Experimental Procedures.” The agonist CCL3 was arbitrarily defined as the reference with a bias factor of 0. The values represent the means ± S.E. of at least three independent experiments. ND, not determined.

Bias (β)	Gα_i1:Gα_ob	Gα_i1:Gα₁₂	Gα_i1:Arr	Gα_i1:cAMP	Gα_i1:Ca	Gα_ob:G12	Gα_ob:Arr	Gα_ob:cAMP	Gα_ob:Ca	Gα₁₂:Arr	Gα₁₂:cAMP	Gα₁₂:Ca	Arr:cAMP	Arr:Ca	cAMP:Ca
CCL3	0.00 ± 0.76	0.00 ± 0.67	0.00 ± 0.60	0.00 ± 0.58	0.00 ± 0.56	0.00 ± 0.68	0.00 ± 0.62	0.00 ± 0.60	0.00 ± 0.58	0.00 ± 0.50	0.00 ± 0.47	0.00 ± 0.45	0.00 ± 0.37	0.00 ± 0.34	0.00 ± 0.30
CCL4	−0.06 ± 0.61	0.80 ± 0.57	0.59 ± 0.50	0.93 ± 0.50	−0.54 ± 0.48	0.86 ± 0.55	0.65 ± 0.48	0.99 ± 0.47	−0.48 ± 0.46	−0.21 ± 0.43	0.13 ± 0.42	−1.34 ± 0.41	0.34 ± 0.32	−1.13 ± 0.30	−1.47 ± 0.29^a
CCL5	−0.33 ± 0.74	0.47 ± 0.70	1.58 ± 0.68	1.01 ± 0.66	0.34 ± 0.63	0.80 ± 0.53	1.91 ± 0.50^a	1.35 ± 0.48	0.67 ± 0.44	1.11 ± 0.43	0.55 ± 0.40	−0.13 ± 0.36	−0.56 ± 0.37	−1.24 ± 0.32	−0.68 ± 0.28
CCL8	0.13 ± 0.64	0.72 ± 0.65	1.72 ± 0.50	2.59 ± 0.49^a	0.03 ± 0.44	0.59 ± 0.71	1.59 ± 0.58	2.46 ± 0.56^a	−0.10 ± 0.53	0.99 ± 0.60	1.87 ± 0.58	−0.70 ± 0.55	0.88 ± 0.41	−1.69 ± 0.36^a	−2.56 ± 0.33^a
CCL13	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND

^a Bias factors with statistically significant difference with the CCL3 reference (p < 0.05).