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. 2015 Jan 22;290(15):9542–9554. doi: 10.1074/jbc.M114.596098

TABLE 5.

Bias factors at CCR2

The bias factors were calculated as described under “Experimental Procedures.” The agonist CCL2 was arbitrarily defined as the reference with a bias factor of 0. The values represent the means ± S.E. of at least three independent experiments. ND, not determined.

Bias (β) i1ob i1:Gα12 i1:Arr i1:cAMP i1:Ca ob:Gα12 ob:Arr ob:cAMP ob:Ca 12:Arr 12:cAMP 12:Ca Arr:cAMP Arr:Ca cAMP:Ca
CCL2 0.00 ± 0.46 0.00 ± 0.49 0.00 ± 0.43 0.00 ± 0.62 0.00 ± 0.44 0.00 ± 0.32 0.00 ± 0.52 0.00 ± 0.49 0.00 ± 0.24 0.00 ± 0.27 0.00 ± 0.52 0.00 ± 0.30 0.00 ± 0.46 0.00 ± 0.17 0.00 ± 0.64
CCL7 −0.72 ± 0.58 −0.26 ± 0.61 0.27 ± 0.56 −0.83 ± 0.68 ND 0.46 ± 0.32 0.98 ± 0.48 −0.11 ± 0.44 0.72 ± 0.26 0.52 ± 0.29 −0.57 ± 0.48 0.26 ± 0.33 −1.10 ± 0.41 −0.26 ± 0.22 0.83 ± 0.56
CCL8 −1.09 ± 0.83 ND 0.80 ± 0.73 −0.07 ± 0.81 ND ND 1.89 ± 0.96a 1.02 ± 0.53 ND ND ND ND −0.87 ± 0.37 ND ND
CCL13 −0.86 ± 0.60 ND 0.26 ± 0.54 ND ND ND 1.12 ± 0.57 ND ND ND ND ND ND ND ND

a Bias factors with statistically significant differences with the CCL2 reference (p < 0.05).