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. 2015 Apr 10;5:9621. doi: 10.1038/srep09621

Figure 1. Transplantation of s-NSCs or o-NSCs reduces infarct volume after ischemic injury.

Figure 1

Mice received transplantation of o-NSCs or s-NSCs or vehicle injection 2 hours after MCAO. Brain sections were immunostained for MAP2 at 7 and 28 days after MCAO. (a–b) Representative MAP2-stained coronal sections showed smaller infarct or reduced cerebral tissue atrophy at 7 d (a) and 28 d (b) after MCAO in mice receiving transplantation of NSCs. (c) Infarct volume and tissue atrophy were significantly reduced at 7 and 28 days after MCAO, respectively, as compared to vehicle-treated mice. Data are mean ± SEM, n = 7/group, #p ≤ 0.05, ##p ≤ 0.01 versus vehicle; $$p ≤ 0.01 versus o-NSC. (d) Representative brain images illustrate less brain tissue loss in NSC-treated mice than in vehicle-treated mice.