Table 2.

Results of Cox Proportional Hazards Models Examining the Relationship Between the L/E_SPTI at Baseline and the Risk of Heart Failure During Follow‐Up (Number of Events=135)

	Hazard Ratio Per 1% Increase in L/ESPTI (95% CI)	Standardized Hazard Ratio (95% CI)*	P Value
Model 1	1.22 (1.15 to 1.29)	1.74 (1.49 to 2.04)	<0.0001
Model 2	1.27 (1.18 to 1.36)	1.95 (1.60 to 2.36)	<0.0001
Model 3	1.22 (1.14 to 1.32)	1.76 (1.44 to 2.16)	<0.0001
Model 4	1.24 (1.14 to 1.34)	1.82 (1.45 to 2.28)	<0.0001

Model 1 is unadjusted (n=6124). Model 2 (n=6124) is adjusted for age, ethnicity, gender, and heart rate. Model 3 (n=6107) is additionally adjusted for diabetes mellitus, systolic and diastolic blood pressure, and body mass index. Model 4 (n=6098) is additionally adjusted for antihypertensive medication use, total cholesterol, HDL cholesterol, current smoking, estimated glomerular filtration rate, aortic augmentation index, and aortic‐to‐radial pulse pressure amplification. HDL indicates high‐density lipoprotein; L/E_SPTI, late/early systolic pressure–time integral.

^*The standardized hazard ratio (HR) is the HR per 1‐SD increase in L/E_SPTI. The SD for L/E_SPTI is 2.8%.