Table 1.

Effective Arterial Elastance (Ea) and End‐Systolic Elastance (Ees) Values Employed for the P/V Loop Model for Each Patient Group at Rest and With Exercise (Group Average Values Used)

	Normal Control (V0=10)		Post‐PEA (V0=−8)		CTEPH (V0=14)		Post‐PEA+Sildenafil (V0=−8)
	Rest	Ex	Rest	Ex	Rest	Ex	Rest	Ex
Ea, mm Hg/mL	0.11	0.21	0.43	0.69	1.11	1.53	0.38	0.52
Ees, mm Hg/mL	0.17	0.69	0.43	0.77	0.78	0.88	0.43*	0.77
Ees/Ea	1.5†	3.2	1.0†	1.1	0.7†	0.06	1.1†	1.4

CTEPH indicates chronic thromboembolic pulmonary hypertension; mPAP, mean pulmonary artery pressure; PEA, pulmonary endarterectomy; sPAP, systolic pulmonary artery pressure.

^*Assumes no change in Ees at rest with sildenafil administration.

V0 and Ees are calculated by presuming^† coupling ratios (Ees/Ea) of 1.5 for controls,¹⁸ 1.0 for post‐PEA patients,¹⁹ and 0.7 for CTEPH patients.²⁰ Ea for normal controls calculated by mPAP/stroke volume (SV); Ea for post‐PEA and CTEPH patients calculated by sPAP/SV.^15–16 V0 presumed unchanged within each patient group from rest to exercise.