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. 2015 Apr 8;15:239. doi: 10.1186/s12885-015-1210-4

Figure 3.

Figure 3

Barasertib inhibits expression of Aurora kinase B and phosphorylation of INCENP. Western blots showing protein expression of Aurora kinase B, INCENP and phosphorylated INCENP (p-INCENP) in lysates from parental (T47D) and fulvestrant resistant (182R-1 and 182R-2) cells treated with barasertib (50 nM) or DMSO (control) for the indicated time periods (4–96 hours). Heat shock protein 70 (Hsp70) was used as loading control.