Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Mar 10;17(1):53. doi: 10.1186/s13075-015-0582-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Bian et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Accelerated and more severe dacryoadenitis in CD25/IL-17 DKO LG. (A) Representative images of H&E-stained LG from mice aged 4 to 16 weeks (W). The square is a higher magnification of the area underneath. Scale bar = 100 μm. (B) Percent area of lymphocytic infiltration measured in digital images of H&E-stained LG sections from IL-17KO, CD25/IL-17 DKO and CD25KO mice at 4, 8, 12, and 16 W. (C) EGF concentration measured in tear washings from different strains. ^* P <0.05;^** P <0.01, ^*** P <0.001; ^**** P <0.0001 within strain comparison vs. 4 W. ^{^} P <0.05; ^{^^} P <0.01, ^{^^^} P <0.001; ^{^^^^} P <0.0001 interstrain comparison. CD25/IFN-γ DKO, CD25^−/−IFN-γ^−/−; CD25KO, CD25 knockout; DKO, double knockout; EGF, epidermal growth factor; H&E, hematoxylin and eosin; IL, interleukin; IL-17KO, IL-17 knockout; KO, knockout; LG, lacrimal gland.