Table 3.
Distribution of PfCRT and PfMDR1 haplotypes in the study population 2003 – 2006
| Year | |||||
|---|---|---|---|---|---|
| 2003 | 2004 | 2005 | 2006 | TOTAL | |
| PfCRT amino acid positions 72–76 | |||||
| CVMNK only | 0.0% (0) | 3.4% (4) | 7.9% (6) | 0% (0) | 4.3% (10) |
| CVIET only | 96.9% (31) | 94.9% (111) | 89.5% (68) | 100% (9) | 93.6% (219) |
| CVMNK & CVIET mixed | 3.1% (1) | 1.7% (2) | 2.6% (2) | 0% (0) | 2.1% (5) |
| Number of samples | 32 | 117 | 76 | 9 | 234 |
| PfMDR1 amino acid positions 86, 184, 1042, 1246 | |||||
| YYNY only | 67.7% (12) | 67.8% (59) | 66.2% (43) | 75% (6) | 67.4% (120) |
| YYNY mixed* | 5.6% (1) | 11.5% (10) | 9.2% (6) | 0.0% (0) | 9.6% (17) |
| YYND only | 16.7% (3) | 10.3% (9) | 13.8% (9) | 12.5% (1) | 12.4% (22) |
| YYND mixed** | 0.0% (0) | 10.3% (9) | 7.7% (5) | 0.0% (0) | 7.9% (14) |
| Other haplotypes | 11.1% (2) | 6.9% (6) | 9.2% (6) | 12.5% (1) | 8.4% (15) |
| Number of samples | 18 | 87*** | 65*** | 8 | 178*** |
*Mixed with codons of other haplotypes, including 10 YYND (6 in 2004; 4 in 2005).
**Mixed with codons of other haplotypes, including 10 YYNY (6 in 2004; 4 in 2005).
***Total is corrected for the YYNY + YYND mixed samples that are entered twice, as both YYNY mixed and as YYND mixed samples.