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. Author manuscript; available in PMC: 2016 Apr 8.
Published in final edited form as: Cell Host Microbe. 2015 Mar 26;17(4):429–440. doi: 10.1016/j.chom.2015.03.001

Figure 5. Atg16L1 Deletion in Endothelial Cells Confers Susceptibility to S. aureus Mediated Lethality.

Figure 5

(A) Survival curve of Atg16L1fl/fl (controls) and Atg16L1fl/fl-Tie2Cre mice infected i.v. with 107 cfu USA300. n=5–6 mice/group.

(B) Survival curve of Atg16L1fl/fl and Atg16L1fl/fl-Tie2Cre mice inoculated intranasally with 4x108 cfu USA300. n=24 mice for Atg16L1fl/fl and n=15 mice for Atg16L1fl/fl -Tie2Cre.

(C) Survival curve of Atg16L1HM, Atg16L1fl/fl, Atg16L1fl/fl-LyzCre, and Atg16L1fl/fl-CD11cCre mice infected i.v. with 107 cfu USA300. n=10 mice for Atg16L1HM, n=21 mice for Atg16L1fl/fl, n=18 mice for Atg16L1fl/fl-LyzCre, n=9 mice for Atg16L1fl/fl-CD11cCre.

Data represent at least 2 independent experiments. *p<0.05

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