Figure 2.

Protein expression of Nogo-A in injured spinal cord at different time points after injury.

Nogo-A expression was stable and similar between the normal group (normal) and sham-operated group (sham), without significant difference (P > 0.05). The expression of Nogo-A after spinal cord injury in the model group (model) varied dynamically. The expression of Nogo-A in the model group at 24 hours after spinal cord injury was low, and dropped to the lowest level at 3 days, then gradually rose to a peak at 7 days, and gradually declined after 14 days. However, the expression in the model group remained at a high level, which was significantly different from that in the sham group at all time points (*P < 0.05, vs. sham-operated group). Data were expressed as the mean ± SD of three rats in each group. One-way analysis of variance and the least significant difference test were used. h: Hours; d: days.