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. 2015 Apr 3;8:204. doi: 10.1186/s13071-015-0805-6

Table 5.

Published percentages of efficacy results of fipronil or permethrin based products against Ixodes ricinus (geometric means) [17-21]

Active ingredient(s) Days after treatment
Day 2 Day 9 Day 16 Day 23 Day 30 Day 37
Fipronil + permethrin (a) 98% 100% 100% 100% 97% 96%
Fipronil (b) 98.8% 100.0% 100.0% 100.0% 86.3% 77.2%
Fipronil (c) 93.8% 100.0% 100.0% 98.9% 97.9% 94.1%
Imidacloprid + permethrin (d) 67.0% 100.0% 100.0% 99.5% 98.7% 91.6%
Fipronil + amitraz (e) 97.9% 100% 100% 98.1% 97.7% 96.3%
Day 2 Day 7 Day 14 Day 21 Day 28 Day 35
Permethrin (f) 99.1% 99.1% 95.9% 88.5% 87.1% 74.1%
Permethrin (g) - 96.3% 99.5% 90.7% 90.3% 91.3%

(a): Effitix®.

(b): Frontline ® Spot-on Dog Merial [17].

(c): Effipro® Spot-on Virbac SA [17].

(d): Imidacloprid 10% (w/v) / Permethrin 50% (w/v) Spot-on [18].

(e): CertifectTM Merial Limited [21].

(f): Defend® Exspot® Treatment for dogs, Schering-Plough Animal Health Corp., 65% permethrin[19].

(g): Defend® Exspot® Treatment for dogs, Schering-Plough Animal Health Corp., 65% permethrin [20].