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. 2015 Mar 24;16:110. doi: 10.1186/s13063-015-0641-1

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© Irving et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Trial schema for Phase 1 traditional escalation response. CT, computed tomography; DLT, dose-limiting toxicity; FOLFOX, folinic acid/5-fluorouracil/oxaliplatin; QLQ-C30, Quality of Life Questionnaire C-30; RECIST, response evaluation criteria for solid tumours.